Inactivated FABP5 suppresses malignant progression of prostate cancer cells by inhibiting the activation of nuclear fatty acid receptor PPARγ
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Inhibitor SBFI26 suppresses the malignant progression of castration-resistant PC3-M cells by competitively binding to oncogenic FABP5
Castration resistant-prostate cancer is largely impervious to feather hormonal therapy and hence the outlook for patients is grim. Here we use an approach to attach the recently discovered Achilles heel. The experimental treatment established in this study is based on the recent discovery that it is the FABP5-PPARγ-VEGF signalling axis, rather than the androgen receptor pathway, played a domina...
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15 صفحه اولGlipizide suppresses prostate cancer progression in the TRAMP model by inhibiting angiogenesis
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ژورنال
عنوان ژورنال: Genes & Cancer
سال: 2019
ISSN: 1947-6027
DOI: 10.18632/genesandcancer.192